воскресенье, 20 января 2019 г.

More Nephrons Wnted You’ve got around 2 million of them –…


More Nephrons Wnted


You’ve got around 2 million of them – nephrons, tiny filters in your kidneys that clear out the waste products in your blood. The right numbers of nephrons are produced during development by cells called nephron progenitors. A pool of these progenitors is maintained, with a steady stream maturing into different nephron cells. This fine balance is sustained by signalling molecules called Wnts. Researchers dig deeper by focusing on Wnt11, which accumulates at the tips of developing kidney branches where nephron progenitors live. Fluorescent imaging of kidneys from mutant mice lacking Wnt11 (pictured, right) revealed that the progenitors lost their sense of orientation, revealed by the polarised distribution of the protein desmin (green) within these cells being disrupted compared to normal kidneys (left). Mutants also depleted their pool of progenitors faster, resulting in half the number of nephrons and smaller kidneys. Wnt11 is therefore a major player in kidney development.


Written by Lux Fatimathas



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2019 January 20 A Total Lunar Eclipse Video Video Credit &…


2019 January 20


A Total Lunar Eclipse Video
Video Credit & Copyright: Jun Ho Oh (KAIST, HuboLab), Kwon O Chul (TWAN), Jeong ByoungJun (RainbowAstro)


Explanation: Tonight a bright full Moon will fade to red. Tonight’s moon will be particularly bright because it is reaching its fully lit phase when it is relatively close to the Earth in its elliptical orbit. In fact, by some measures of size and brightness, tonight’s full Moon is designated a supermoon, although perhaps the “super” is overstated because it will be only a few percent larger and brighter than the average full Moon. However, our Moon will fade to a dim red because it will also undergo a total lunar eclipse – an episode when the Moon becomes completely engulfed in Earth’s shadow. The faint red color results from blue sunlight being more strongly scattered away by the Earth’s atmosphere. A January full moon, like the one visible tonight, is referred to as a Wolf Moon in some cultures. Tonight’s supermoon total eclipse will last over an hour and be best visible from North and South America after sunset. The featured time-lapse video shows the last total lunar eclipse – which occurred in 2018 July. The next total lunar eclipse will occur only in 2021 May.


∞ Source: apod.nasa.gov/apod/ap190120.html


Castlerigg Stone Circle at late dusk, Photoset 1, Cumbria, 6.1.19.

Castlerigg Stone Circle at late dusk, Photoset 1, Cumbria, 6.1.19.










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Castlerigg Stone Circle at Dusk, Photoset 2, Cumbria, 6.1.19.

Castlerigg Stone Circle at Dusk, Photoset 2, Cumbria, 6.1.19.










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Nether Largie Standing Stones, Kilmartin Glen, Argyll, 12.1.19.

Nether Largie Standing Stones, Kilmartin Glen, Argyll, 12.1.19.









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United Launch Alliance Successfully Launches NROL-71


ULA – Delta IV Heavy / NROL-71 Mission poster.


Jan. 19, 2019


United Launch Alliance Successfully Launches NROL-71 in Support of 
National Security



Delta IV Heavy carrying NROL-71 launch

A United Launch Alliance (ULA) Delta IV Heavy rocket carrying a critical payload for the National Reconnaissance Office (NRO) denoted NROL-71 lifted off from Space Launch Complex-6 on Jan. 19 at 11:10 a.m. PST. The mission is in support of our country’s national defense.


“Congratulations to our team and mission partners for successfully delivering this critical asset to support national security missions,” said Gary Wentz, ULA vice president of Government and Commercial Programs, “thank you to the entire team for their perseverance, ongoing dedication and focus on 100% mission success.”



Delta IV Heavy launches NROL-71

The Delta IV Heavy is the nation’s proven heavy lift launch vehicle, delivering high-priority missions for the National Reconnaissance Office, U.S. Air Force and NASA. With its advanced upper stage, the Delta IV Heavy can take more than 14,000 pounds directly to geosynchronous orbit, as well as a wide variety of complex interplanetary trajectories.


The mission launched aboard a Delta IV Heavy, comprised of three common booster cores each powered by an Aerojet Rocketdyne RS-68A liquid hydrogen/liquid oxygen engine producing a combined total of more than 2.1 million pounds of thrust. The second stage was powered by an AR RL10B-2 liquid hydrogen/liquid oxygen engine.



Delta IV Heavy / NROL-71 Mission patch

NROL-71 is ULA’s first launch in 2019 and 132nd successful launch since the company was formed in December 2006.


ULA’s next launch is the WGS-10 mission for the U.S. Air Force on a Delta IV rocket. The launch is scheduled for March 13, 2019 from Space Launch Complex-37 at Cape Canaveral Air Force Station, Florida.


With more than a century of combined heritage, ULA is the world’s most experienced and reliable launch service provider. ULA has successfully delivered more than 130 satellites to orbit that provide Earth observation capabilities, enable global communications, unlock the mysteries of our solar system, and support life-saving technology.


For more information on ULA, visit the ULA website at https://www.ulalaunch.com/home


Images, Video, Text, Credits: United Launch Alliance (ULA)/SciNews.


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Dunchraigaig Prehistoric Burial Cairn, Kilmartin Glen, Argyll, Scotland, 12.1.19.

Dunchraigaig Prehistoric Burial Cairn, Kilmartin Glen, Argyll, Scotland, 12.1.19.








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Nether Largie Mid Cairn, Kilmartin Glen, Argyll, Scotland, 12.1.19.

Nether Largie Mid Cairn, Kilmartin Glen, Argyll, Scotland, 12.1.19.












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Inside Anxiety Anxiety affects the lives of millions of…


Inside Anxiety


Anxiety affects the lives of millions of people, with many suffering from long-term mental and physical symptoms. Although often treated with psychology-based techniques like cognitive behavioural therapy (CBT), these mouse neurons – reconstructed here in 3D from high-powered microscopy images – offer clues to the how anxiety works at the cellular level. In normal neurons (left), a protein called MeCP2 (artificially-coloured red) hitches a ride into the nucleus (blue) with another protein called importin alpha-5, where it helps to provoke anxious signals. Depriving similar mouse cells of importin alpha-5 traps MeCP2 on the outside (right) – mice without importin alpha-5 are less anxious in stressful situations like escaping a maze. Researchers now hope to use drugs which target related proteins to calm human sufferers, combining this neuroscience with other forms of therapy.


Written by John Ankers



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